Helminth Parasites and the Modulation of Joint Inflammation
نویسندگان
چکیده
منابع مشابه
Helminth Parasites and the Modulation of Joint Inflammation
There is an urgent need to develop better therapeutics for autoimmune and autoinflammatory diseases, of which musculoskeletal disorders such as rheumatoid arthritis are particularly prevalent and debilitating. Helminth parasites are accomplished masters at modifying their hosts' immune activity, and so attention has focused on rodent-helminth model systems to uncover the workings of the mammali...
متن کاملThe Incidence of Helminth Parasites in Donkeys
The faeces of 82 donkeys irrespective of sex and age were collected and examined for any parasitic ova. The faecal sample of68 donkeys were infected with: Strongylus sp. (54.87%), Parascaris sp. (29.26%), Strongyloides sp. (24.39%), Trichonema sp. (15.85%), Oxyuris sp. (8.53%), Gastrodiscus sp. (8.53%), Entamoeba sp. (8.53%), Dictyocaulus sp. (3.65%), and Triodontophorus sp. (2.43%).
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Parasitic infection is highly allergenic, and the present paper illustrates how parasites might disrupt the regulation of IgE synthesis, resulting in heightened Th-2 responses. The study of parasites, and dysregulation of the IgE network, could in turn provide information relating to the aetiology of allergic diseases such as asthma and atopic dermatitis.
متن کاملHelminth parasites of laboratory mice and rats.
Rodents, as mice and rats are the most common laboratory animals used in research and testing. They are seldom investigated for autochthonous ecto- and endoparasites prior their utilization in the experiments. Helminth parasites can alter the interpretation of final results. Pinworms commonly infecting laboratory rodents include mainly the mice pinworms Syphacia obvelata and Aspiculuris tetrapt...
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Parasitic helminth infection remains a global health problem, whilst the ability of worms to manipulate and dampen the host immune system is attracting interest in the fields of allergy and autoimmunity. Much progress has been made in the last two years in determining the cells and cytokines involved in induction of Type 2 immunity, which is generally protective against helminth infection. Inna...
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ژورنال
عنوان ژورنال: Journal of Parasitology Research
سال: 2011
ISSN: 2090-0023,2090-0031
DOI: 10.1155/2011/942616